10 Best Red Yeast Rice Supplements In 2025

Red yeast rice supplements might lower cholesterol levels naturally. It contains fermented rice with Monascus purpureus yeast, which produces a compound similar to the active ingredient in statin drugs. Because of this, red yeast rice products could promote a healthy heart function by reducing LDL or bad cholesterol and possibly improving your lipid profiles.

Many people choose red yeast rice supplements as a healthier option when diet and exercise are not enough. However, not every supplement on the market offers the same quality or strength. Some products might contain helpful amounts of active compounds, while others may fall short or include unwanted ingredients.

This guide lists the 10 best red yeast rice supplements that might support healthy cholesterol levels. If you’re new to red yeast rice products or looking to improve your current routine, this exclusive guide can help you find a suitable option to support your heart health goals.

10 Best Red Yeast Rice For Cholesterol

1. Force Factor Red Yeast Rice + CoQ10

   

   Force Factor Red Yeast Rice + CoQ10 could help promote cardiovascular function by providing 1,200 mg of red yeast rice powder per two capsules. This formula also includes 100 mg of Coenzyme Q10 (CoQ10), a compound your body naturally produces but tends to decline with age and statin use. CoQ10 plays a critical part in energy production within cells and may support heart muscle strength and cardiovascular function. As per the official website, Force Factor Red Yeast Rice + CoQ10 provides antioxidant protection to help combat oxidative stress. The formula is said to be vegan, non-GMO, and made without unnecessary additives.
   

   Pros

   • May support healthy cholesterol levels.
   • Could support metabolic health and lipid balance.
   • Might help reduce inflammation linked to cardiovascular issues

   Cons

   • Might trigger nausea in some people.
   • Some people could experience minor allergic reactions.

2. Nature’s Craft Red Yeast Rice + CoQ10

   

   As per the official website, Nature’s Craft Red Yeast Rice + CoQ10 provides 1,200 mg of red yeast rice extract and 100 mg of Coenzyme Q10 (CoQ10) per two capsules, which may support better cardiovascular function. It could help manage cholesterol levels, particularly by lowering LDL cholesterol while supporting energy production, heart muscle strength, and cellular health.

   Nature’s Craft Red Yeast Rice + CoQ10 may also help decrease plaque buildup in your arteries and improve your blood flow. Managing your LDL cholesterol this way can help lower your risk of heart disease. CoQ10 in Nature’s Craft Red Yeast Rice + CoQ10 might support your heart’s strength and ability to pump efficiently. This formula could also help protect your cells from oxidative stress and inflammation, which helps maintain long-term cardiovascular health.
   

   Pros

   • May help maintain your heart function.
   • Contains naturally occurring monacolin K (similar to lovastatin).
   • Could also support healthy blood circulation.

   Cons

   • Benefits are subtle and slow to appear.
   • No significant energy boost despite CoQ10.
   • Requires long-term use for visible results.

3. MAV NUTRITION Red Yeast Rice

   

   MAV Nutrition Red Yeast Rice is designed to support your heart function by delivering 1,200 mg of red yeast rice powder per three capsules. It may help assist in keeping cholesterol levels within a healthy range when combined with proper diet and lifestyle choices.

   As per the official website, MAV Nutrition Red Yeast Rice includes 100 mg of Coenzyme Q10 (CoQ10), an antioxidant essential for energy production in heart cells. This might also help reduce oxidative stress and support muscle strength, which is especially important for those taking statin-like compounds, which can deplete natural CoQ10 levels.

   The makers also added 50 mg of niacin (vitamin B3) in MAV Nutrition Red Yeast Rice, which could support healthy cholesterol metabolism and cardiovascular function. It also features 320 mg of flaxseed oil powder, providing 72 mg of alpha-linolenic acid (ALA), a plant-based omega-3 fatty acid that might support circulation, heart rhythm, and muscle function.
   

   Pros

   • May help reduce triglyceride levels.
   • Could help assist in managing total cholesterol.
   • Might support endothelial function.

   Cons

   • The pills have a strong, unpleasant taste and smell that lingers, causing gagging for some users.
   • You need to take three capsules per dose, which can be inconvenient and intensify the taste issue.

4. Zazzee Red Yeast Rice with CoQ10

   

   Zazzee Red Yeast Rice with CoQ10 claims to support your heart function and cholesterol levels. According to the official site, each bottle contains 150 vegetarian capsules, offering a generous 3+ month supply. The formula provides you with 1,200 mg of red yeast rice extract per two capsules, derived from a 20:1 potent extract that equals around 24,000 mg strength per serving.

   Zazzee Red Yeast Rice with CoQ10 also features 60 mg of Coenzyme Q10 (CoQ10) for cardiovascular energy support. Niacin (Vitamin B3) in this formula may help manage cholesterol levels while increasing HDL cholesterol and lowering triglycerides, contributing to a balanced cholesterol profile. This makes the formula more effective by supporting cholesterol metabolism. The makers also added 2.5 mg of BioPerine® in Zazzee Red Yeast Rice with CoQ10, a black pepper extract, which can help enhance the absorption of all these nutrients. This means your body can better utilize the ingredients, improving the supplement’s effectiveness.
   

   Pros

   • Zazzee is said to be a 100% vegetarian, citrinin-free formula.
   • It is produced in FDA-registered and GMP-certified facilities for safety.
   • It could help reduce oxidative stress.

   Cons

   • Some people may notice HDL drop and triglycerides rise despite taking the supplement.
   • Ingredient potency is uncertain due to a lack of clear standardization.

5. NatureBell Red Yeast Rice

   

   NatureBell offers a potent 2-in-1 formula combining Red Yeast Rice and CoQ10 to support heart health. It provides a potent 2,400 mg herbal equivalent of Red Yeast Rice extract. Alongside this, you also get 100 mg of Coenzyme Q10 (CoQ10) in this formula, which might support cardiovascular energy production and brain health and combat oxidative stress.

   With 240 natural vegetarian capsules per bottle and a recommended serving size of two capsules, this supply lasts approximately four months (120 servings). The blend of CoQ10 and Red Yeast Rice might promote healthy cholesterol levels while enhancing energy and cognitive function.
   

   Pros

   • Might help support arterial flexibility.
   • May aid in lowering inflammation markers.
   • Could help promote vascular health.
   • May aid in lowering inflammation markers.

   Cons

   • Smaller capsule size might correspond to a lower dosage, possibly needing multiple pills for effectiveness.
   • Could make you feel dizzy.

6. Thorne Red Yeast Rice + CoQ10

   

   According to the official website, Thorne’s Red Yeast Rice + CoQ10 provides 600 mg of Red Yeast Rice extract per capsule, which may help maintain lipid balance.

   Thorne’s Red Yeast Rice + CoQ10 also features 15 mg of Coenzyme Q10 (CoQ10) per capsule, which might support antioxidant protection and help replenish CoQ10 levels, which naturally decline during cholesterol synthesis.

   Thorne Red Yeast Rice + CoQ10 contains phytosterols such as beta-sitosterol, campesterol, and stigmasterol, along with isoflavones and trace minerals, all contributing to better cardiovascular function. These phytosterols are naturally occurring compounds that can help lower cholesterol levels by blocking their absorption in the digestive tract, which may contribute to improved heart health over time.
   

   Pros

   • May help regulate lipid metabolism.
   • Could support liver health with proper dosing.
   • May contribute to reduced risk of plaque buildup.

   Cons

   • Effectiveness may vary, leaving some users unsure if it lowers cholesterol.
   • Higher price compared to similar products with more CoQ10.

7. ForestLeaf Red Yeast Rice

   

   ForestLeaf Red Yeast Rice provides 1,215 mg of Red Yeast Rice extract per three capsules. It is enhanced with 225 mg of Alpha Lipoic Acid that might help neutralize free radicals, support healthy blood sugar levels, improve detoxification, and aid nerve function.

   As per the official website, ForestLeaf Red Yeast Rice includes 60 mg of Coenzyme Q10 (CoQ10), which is critical for protecting cells from oxidative damage and supporting heart function, physical performance, and recovery.

   ForestLeaf Red Yeast Rice also features 300 mg of Organic Flaxseed, which provides omega-3 fatty acids and natural fiber. Flaxseed offers anti-inflammatory benefits, may support digestive function, and promote nutritional balance. The makers advise taking three ForestLeaf Red Yeast Rice capsules, preferably with a meal daily or as suggested by the doctor.
   

   Pros

   • May assist in maintaining healthy blood pressure.
   • Can support your cardiovascular efficiency.
   • Could offer statin-like benefits without a prescription.

   Cons

   • There’s a risk of allergic reactions for certain people.
   • The supplement can cause an unpleasant urine odor.
   • Some may find the price higher than expected.

8. Puritan’s Pride Red Yeast Rice

   

   According to the official website, Puritan’s Pride Red Yeast Rice features 600 mg per capsule, which may assist in managing heart health and supporting cholesterol management. It could help maintain healthy LDL cholesterol levels. Puritan’s Pride Red Yeast Rice also has compounds like ankaflavin and monascin due to its red yeast rice content, which are linked to antioxidant and anti-inflammatory activity. These bioactives may improve blood vessel flexibility and reduce markers like hs-CRP, supporting long-term heart function. The makers suggest taking two Puritan’s Pride capsules once or twice daily with food, not exceeding four capsules in 24 hours.
   

   Pros

   • May help prevent cholesterol oxidation.
   • Could help improve exercise endurance by enhancing circulation.
   • Might help promote better nutrient delivery through improved blood flow.

   Cons

   • Some people might experience mild side effects typical of red yeast rice, such as digestive discomfort.
   • Results could vary, and not everyone may experience the same effects.

9. Natgrown Red Yeast Rice with CoQ10

   

   Natgrown Red Yeast Rice with CoQ10 could help naturally support cardiovascular health and vitality. It also provides 1,200 mg of Red Yeast Rice alongside 100 mg of Coenzyme Q10 (CoQ10) per two capsules, which can support optimal heart and circulatory function.

   As per the official website, Natgrown Red Yeast Rice with CoQ10 could help promote healthy cholesterol levels, particularly by helping to maintain LDL cholesterol within a normal range. CoQ10, in this formula, might also support mitochondrial energy production, supporting cellular function and endurance.

   The makers state that Natgrown Red Yeast Rice with CoQ10 may help aid in muscle performance and daily energy levels. It could also help defend against oxidative stress caused by free radicals while helping you maintain healthy cells and supporting your body’s natural defenses against environmental and metabolic stressors.
   

   Pros

   • May help prevent cholesterol oxidation.
   • Could help support healthy aging.
   • Might help improve exercise endurance by enhancing circulation.

   Cons

   • Effects are subtle and not noticeable to many users.
   • Its capsule size can be difficult to swallow for some people.

10. Totaria Red Yeast Rice

    

    Totaria Red Yeast Rice claims to provide cholesterol and cardiovascular support by combining 2,000 mg of Red Yeast Rice with 100 mg of Coenzyme Q10 (CoQ10), 200 mg of Citrus Bergamot, 100 mg of Hawthorn, and 65 mg of essential multivitamins per two capsules.

    As per the official website, Totaria Red Yeast Rice can help promote optimal heart health and energy production and enhance your vitality. The addition of Citrus Bergamot in Totaria Red Yeast Rice is rich in flavonoids like brutieridin and melitidin, which can further improve your cholesterol balance by influencing lipid metabolism and supporting HDL cholesterol levels.

    Totaria Red Yeast Rice could also promote cellular energy production, supporting cardiovascular, muscular, and neurological health. The CoQ10 in this formula might help sustain your energy levels and protect cellular integrity, especially in tissues with high energy demands like the heart.
    

    Pros

    • Could help promote better nutrient delivery through improved blood flow.
    • May aid in detoxification through enhanced liver function.
    • Might support your cognitive health by supporting better blood flow.

    Cons

    • No confirmation of citrinin testing raises safety concerns for kidney health.
    • Lacks organic certification and pesticide-free assurance.
    • Insufficient product details force users to research purity and sourcing.

Side Effects of Red Yeast Rice For Cholesterol

1. Possibility of Liver damage

   Red yeast rice supplements contain monacolin K, a compound identical to the prescription statin lovastatin. This ingredient lowers cholesterol by inhibiting an enzyme in the liver responsible for cholesterol production. However, because of this similarity, red yeast rice for cholesterol carries the same risk of liver damage as statins. Excessive or prolonged use, especially with unregulated products that vary in monacolin K content, can cause liver injury, as shown by elevated liver enzymes (ALT, AST). Early warning signs include fatigue, abdominal pain, jaundice, dark urine, and easy bruising.

2. May Cause Muscle damage

   Another significant potential side effect of red yeast rice products is muscle damage, which can manifest as symptoms ranging from mild soreness and stiffness to more severe myopathy, a general term for muscle disease or dysfunction. This risk arises primarily because monacolin K, the active compound in red yeast rice supplements, can interfere with your body’s synthesis of coenzyme Q10 (CoQ10). CoQ10 is an essential compound involved in mitochondrial energy production within muscle cells. When levels of CoQ10 are depleted, muscle tissue could struggle to meet its energy demands, leading to muscle fatigue, cramps, pain (myalgia), and weakness, particularly in the legs, back, and shoulders.

   The onset of symptoms may occur within weeks or develop gradually over time, and can sometimes be misattributed to exercise or aging. These effects are usually reversible upon discontinuation of the supplement, but if left unaddressed, persistent muscle stress could impact mobility or daily functioning.

3. May Cause Rhabdomyolysis

   Rhabdomyolysis is known as a potentially life-threatening complication that can be triggered by red yeast rice supplements, especially when taken in high doses or combined with certain medications. This condition occurs when skeletal muscle fibers break down rapidly, releasing their internal contents, particularly myoglobin, a muscle protein, into the bloodstream. Excess myoglobin can overwhelm your kidneys’ filtration system, increasing the chance of acute kidney injury or even renal failure if not treated promptly.

   Though uncommon, rhabdomyolysis is considered one of the most serious adverse effects linked to monacolin K, the statin-like compound naturally found in red yeast rice. Symptoms of rhabdomyolysis often develop suddenly and may include severe muscle pain, swelling, muscle weakness, and dark urine that resembles tea or cola in color. Additional signs may include fatigue, nausea, vomiting, fever, or mental confusion, which indicate systemic stress and potential toxicity.

   Certain factors may increase the risk of developing this condition, which includes taking excessive amounts of red yeast rice, using it alongside prescription statins or CYP3A4 inhibitors (such as some antibiotics, antifungals, or grapefruit juice), and having pre-existing kidney or liver issues. Intense physical activity may also raise the likelihood of muscle breakdown, particularly when combined with red yeast rice supplementation.

How Did We Evaluate The Best Red Yeast Rice?

1. Brand Reputation

   Based on available ratings, Force Factor leads in overall brand reputation for red yeast rice supplements, backed by an A+ rating from the BBB. This suggests strong customer service and complaint resolution. However, currently, it does not have Trustpilot reviews.

   Nature’s Craft follows with a moderate 3.8 Trustpilot rating. While it lacks a BBB profile, consistent customer feedback indicates general satisfaction, making it a reasonably trustworthy option.

   Thorne lands in the middle with a C+ BBB rating due to nine complaints, including two unresolved. Despite its broader recognition in the supplement space, this BBB track record raises concerns.

   Puritan’s Pride performs poorly, with a 1.4 Trustpilot rating and no BBB presence, pointing to consistent customer dissatisfaction and unresolved issues that significantly damage trust.

   The remaining brands, such as MAV Nutrition, Zazzee, NatureBell, ForestLeaf, Natgrown, and Totaria, have no presence on either BBB or Trustpilot. Their lack of third-party validation makes it difficult to assess quality or reliability. In a market where credibility is key, this absence puts them at the bottom in terms of brand reputation.

2. Value for Money

   We evaluated these red yeast rice supplements by comparing the total price, capsule count, the inclusion of CoQ10, and overall value per dose.

   Puritan’s Pride ranked highest with a buy-one-get-one-free offer at $18.99 for 240 capsules, just $0.08 per capsule. Nature’s Craft came in second, offering a combination of red yeast rice and CoQ10 at $12.99 for 120 capsules ($0.11 per capsule), making it the most affordable dual-ingredient option. Zazzee, priced at $22.97 for 150 capsules ($0.15 per capsule), and Natgrown at $19.75 for 120 capsules ($0.16 per capsule), also provided strong value with both key ingredients included. NatureBell, though it lacks CoQ10, offered long-term savings with 240 capsules for $27.95, equaling $0.12 per capsule.

   Force Factor’s product at $22.48 for 120 capsules ($0.19 per capsule with CoQ10) was slightly less competitive compared to similar dual-ingredient options. MAV Nutrition offered 90 capsules for $14.95 ($0.17 per capsule) but didn’t include CoQ10, limiting its value. Totaria charged $20.99 for 120 capsules ($0.17 per capsule), and ForestLeaf was priced at $21.95 for 90 capsules ($0.24 per capsule), both providing only red yeast rice, making them less appealing from a cost-benefit standpoint.

   Thorne’s supplement, while from a premium brand, was priced at $42 for 120 capsules, or $0.35 per capsule. Despite its reputation for quality and clean formulations, the price makes it the least cost-effective choice in this group, especially when compared to more affordable products with similar ingredients.

Frequently Asked Questions

1. Can red yeast rice replace prescription cholesterol medications?
   Red yeast rice could lower cholesterol naturally, but it should not replace prescribed medicines without medical supervision.
2. Do red yeast rice supplements interact with other medications?
   Red yeast rice supplements can interact with cholesterol-lowering drugs, blood thinners, and certain other medications, so consult a doctor before use.
3. How is red yeast rice different from synthetic statins?
   Red yeast rice has naturally occurring monacolin K, which is said to be identical to the active ingredient in some statins but comes in smaller, variable amounts, making it less potent but often with fewer side effects.
4. Are red yeast rice supplements legal and approved by health authorities?
   Red yeast rice supplements are generally legal as dietary supplements, but the FDA regulates them differently than drugs. Some products with high monacolin K levels may be restricted.

Conclusion

Red yeast rice may support healthy cholesterol levels through the monacolin K compound, known to inhibit cholesterol production in the liver. Some of these products also include additional ingredients like CoQ10 and antioxidants to enhance cardiovascular support and reduce potential side effects.

However, because monacolin K is chemically similar to prescription statins, these supplements may carry similar risks, including muscle pain, liver enzyme changes, and possible interactions with medications. Variability in monacolin K content between supplements can affect both effectiveness and safety. Some people might also experience side effects related to other ingredients in the supplements.

Red yeast rice supplements should be considered as part of a broader approach for managing cholesterol, which includes diet and exercise. It is advisable to consult a doctor before use, particularly if you have existing health conditions, take other medicines, or are pregnant or nursing.