7 Best At-Home STD Test Kits in 2025

Regular STD testing is important for maintaining optimal health, yet many people find the process intimidating. At-home STD test kits can make it easier, more private, and more comfortable than getting it done at urgent care. It can help with regular screening, which is essential for early detection and treatment.

In this guide, we evaluate the Best At-Home STD test kits, focusing on accuracy, ease of use, and customer support. It also explains if At-Home STD test kits could be effective in providing you with high-quality care that can help you take control of your sexual health or not.

7 Best At-Home STD Tests in 2025

1. myLAB Box Uber Box

   

   The myLAB Box Uber Box detects Chlamydia, Gonorrhea, Hepatitis C (Hep C), HIV (I & II), Syphilis, Trichomoniasis (Trich), and Herpes Simplex Virus Type II (HSV-2). Many of these infections can remain asymptomatic, making regular testing essential for your sexual health.

   The kit includes multiple sample collection methods. Men provide a urine sample, while women use a vaginal swab. A finger-prick blood sample is also required for detecting certain infections like HIV and Syphilis. The myLAB Box Uber Box also has clear, step-by-step instructions, and you can return the samples in a postage-paid box for processing.

   As per the official site, myLAB Box partners with CAP and CLIA-certified laboratories, ensuring that test results meet national standards. The service is also HIPAA-compliant, guaranteeing privacy and security.

   myLAB Box also works as a free telemedicine consultation for people who receive positive test results. A licensed physician will then review the results and, when appropriate, provide prescriptions for treatment for conditions like Chlamydia, Gonorrhea, Trichomoniasis, Bacterial Vaginosis, Yeast Infections, Genital Herpes, or Urinary Tract Infections (UTIs). This process ensures that users receive timely medical care.

   While the test is highly accurate, the FDA has cautioned that HSV-2 serological (antibody) tests can sometimes produce false-positive results, making confirmatory testing necessary.

   With a price of $199, the myLAB Box Uber Box supports FSA and HSA payment options, making it easier for people to prioritize health.
   

   Pros

   • Detects HIV, Syphilis, HSV-2, and other common STIs.
   • Provides multiple sample collection options.
   • Includes prepaid return shipping.
   • Ensures privacy with HIPAA compliance.

   Cons

   • Does not accept insurance, FSA, or HSA.
   • Kits expire within 6 to 12 months.
   • No international shipping is available.

2. Simple Healthkit Common STD Test

   

   The Simple HealthKit Common STD Test lets you collect the urine sample at home and send it to a certified lab for testing. After collecting the sample, you mail it using a prepaid return label. Results are usually available within 24 to 48 hours via a secure, HIPAA-compliant online portal, ensuring your privacy.

   You can also receive complimentary follow-up care with a licensed healthcare provider, including guidance on the next steps and assistance with obtaining prescriptions.

   The Simple HealthKit Common STD Test is physician-approved and eligible for payment through Health Savings Accounts (HSA) and Flexible Spending Accounts (FSA), making it more accessible.

   The Simple HealthKit Common STD Test helps you to take control of your sexual health by offering a private and efficient approach to STI screening, helping to prevent STI transmission.
   

   Pros

   • Certified lab analysis.
   • Prepaid return label for mailing.
   • Results in 24 to 48 hours.
   • Secure, HIPAA-compliant portal.
   • Free follow-up with a healthcare provider.
   • HSA/FSA is eligible.

   Cons

   • Accuracy concerns due to sample collection errors or shipping delays.
   • Delayed sample processing, leading to extended uncertainty.
   • Potentially high cost and limited insurance coverage.

3. Everlywell STD Test

   

   The Everlywell STD Test helps you screen five prevalent sexually transmitted infections (STIs), including Chlamydia, Gonorrhea, Hepatitis C (HCV), Syphilis, and Trichomoniasis. The test kit arrives in packaging that may ensure privacy. It includes a finger prick tool for blood samples and materials for urine collection. Once you’ve collected the samples, you can send them to Everlywell’s lab using the prepaid shipping label provided. Results can be securely accessed through Everlywell’s HIPAA-compliant online platform, ensuring both confidentiality and easy access.

   Everlywell provides a consultation with an independent, board-certified physician who can discuss the results, provide guidance on the next steps, and, if appropriate, prescribe treatment. This integrated approach may help streamline the process of testing and potential treatment, offering you a convenient healthcare experience.
   

   Pros

   • Consultation with a board-certified physician for results discussion and treatment guidance.
   • Discreet packaging ensures privacy.
   • Eligible for HSA and FSA payment.

   Cons

   • Only five STIs are tested, which may not cover all potential concerns.
   • Finger prick and urine collection may be uncomfortable or difficult for some users.
   • While a doctor consult is included, it’s remote, which may not feel as reassuring as an in-person visit.

4. Indicaid Health Sexual Health 2

   

   As per its official site, The Indicaid Health Sexual Health 2 enables you to test for Chlamydia and Gonorrhea. The kit includes easy-to-read instructions, a transfer pipette, a specimen tube, a urine collection cup, a specimen bag, and a pre-labeled next-day return envelope.

   The testing process includes registering the kit online, collecting the urine sample using the provided materials, packaging the specimen, and sending it to the laboratory using the pre-labeled return envelope. The Indicaid Health Sexual Health 2 Kit comes with detailed instructions are included to ensure proper sample collection and handling.
   

   Pros

   • Tests for Chlamydia and Gonorrhea.
   • Comprehensive Kit with all necessary materials.
   • Easy to use with clear instructions.
   • Pre-Paid Return Envelope for quick sample submission.

   Cons

   • Samples can only be shipped from Mondays to Thursdays.
   • The test is not intended for use by pregnant women.
   • Privacy concerns with insurance.

5. LetsGetChecked STD Testing

   

   LetsGetChecked offers a range of at-home STD testing kits, including their Simple 2, Standard 5, and Complete 8 kits. Their most popular option, the Standard 5 test, screens for Chlamydia, Gonorrhea, Hepatitis B, Syphilis, and Trichomoniasis. You can order your chosen kit online, collect the required sample at home, and return it using the prepaid shipping label. Samples are analyzed in certified laboratories, with confidential results available within approximately 2-5 days. If a test detects an infection, a nurse will call to discuss treatment options and provide support.
   

   Pros

   • Standard 5 test screens for multiple infections.
   • Convenient online ordering and at-home sample collection.
   • Certified laboratory analysis.
   • Confidential results within 2-5 days.
   • Provides follow-up virtual consultation.

   Cons

   • LetsGetChecked does not ship to all U.S. states, including Rhode Island, New Jersey, and Alaska.
   • High cost, with prices ranging from $40 to several hundred dollars.
   • Virtual consultations may not fully replicate in-clinic support.

6. 247Labkit Standard Kit

   

   The 247Labkit Standard Kit can help detect Chlamydia, Gonorrhea, and Trichomoniasis. With a fast turnaround, results are typically available within 1 to 2 days after the sample reaches the lab. The kit includes a urine collection cup, specimen bag, transport tube, pipette, and a prepaid shipping label. The 247Labkit uses advanced diagnostic technology to provide medical-grade accuracy.
   

   Pros

   • Fast turnaround time after the sample reaches the lab.
   • Utilizes advanced diagnostic technology for medical-grade accuracy.
   • The lab conducting tests is CLIA-certified, ensuring reliability.
   • Requires simple swab or urine collection.

   Cons

   • Limited to testing for Chlamydia, Gonorrhea, and Trichomoniasis.
   • Risk of incorrect results due to improper sample collection.
   • Only detects current infections, not past or recurring ones.
   • No in-person consultation or professional medical guidance.

7. STDcheck

   

   STDCheck enables you to find a nearby lab where you can get tested without the need for an appointment. Tests are quick, typically taking just a few minutes, and results are delivered online in 1 to 2 days.

   As per the official site, STDCheck has a 10-test panel, which screens for a wide range of sexually transmitted infections, which includes HIV, syphilis, gonorrhea, chlamydia, herpes, and hepatitis A, B, and C. This panel may help you provide a thorough evaluation of your sexual health.

   STDCheck offers the only FDA-approved HIV RNA Early Detection Test, which uses advanced technology to detect the virus in its early stages, even before antibodies are present.

   After ordering your test online, you visit a nearby testing center where you provide a urine or blood sample. There’s no paperwork to complete, and no questions are asked, which may helo to ensure a discreet experience.

   Results are provided through their secure online portal, and if your test results are positive, you can schedule a follow-up consultation with a physician who may prescribe treatment or refer you to a specialist.
   

   Pros

   • No appointment is needed. You can find a nearby lab for testing.
   • Quick tests typically take just a few minutes.
   • Offers a 10-test panel that screens for a wide range of STIs.

   Cons

   • No health insurance acceptance; tests must be paid out-of-pocket.
   • No at-home testing kits; tests require a visit to a testing center.
   • Limited STI coverage (does not test for mycoplasma genitalium and trichomoniasis).

Limitations of At-home STD Test

1. Limited Range of Tests

   At-home STD tests are convenient and provide privacy, but one of their major limitations is the restricted range of tests they offer. Unlike healthcare facilities or clinics where you can receive a wide variety of screenings based on your needs, at-home tests are usually focused on the most common sexually transmitted infections (STIs).

   Most at-home tests will typically screen for infections like chlamydia, gonorrhea, syphilis, and HIV, which are among the most prevalent and important to diagnose early. However, more specialized STDs like hepatitis, herpes, human papillomavirus (HPV), and trichomoniasis may not be included in standard kits. In some cases, even tests for rare but dangerous STDs like the West Nile virus or certain types of HPV may not be available, which limits the comprehensiveness of the test.

2. Sample Collection Challenges

   The accuracy of an at-home STD test depends on proper collection and handling of samples. In most cases, you are required to take a urine sample, a blood sample (via a finger prick), or a swab from genital area. These tests rely heavily on your ability to follow instructions precisely, which can be challenging, especially without professional guidance.

   Improper sample collection can also provide inaccurate results in at-home testing. For example, Urine samples need to be collected at the right time during the day to ensure the highest concentration of the infection markers is present. If a sample is taken too early or too late in the day, it could lead to a false negative result.

   Blood tests require the correct technique for obtaining the sample, as incorrect handling or storage can lead to inaccurate readings. Similarly, swab tests may not yield correct results if the swab does not come into direct contact with the infection or if it is not collected in the right area.

3. No Immediate Medical Support

   At-home tests offer little to no face-to-face assistance, which can be particularly concerning when you are unsure about the testing process, how to properly collect a sample, or what steps to take after receiving the results.

   For example, if you are confused about the sample collection process or whether you have followed the instructions correctly, you are left to rely on written instructions or customer service assistance from the testing company. While customer service representatives can answer basic questions, they are not trained medical professionals who can provide personalized advice based on a person’s specific health history or concerns.

   After receiving test results, if they are positive, there is no immediate access to a healthcare professional who can discuss treatment options or provide emotional support. Many at-home testing services offer a follow-up consultation, but the lack of on-the-spot interaction can delay treatment, and you may feel isolated or confused about the next steps.

4. No Immediate Treatment Options

   At-home STD tests can detect infections, but they do not provide immediate treatment. If you test positive for an infection, you will typically need to visit a healthcare provider for treatment or a prescription. While some at-home testing services offer consultations with doctors to discuss the results and suggest treatment, this still requires additional steps and time.

   The delays in treatment can allow the infection to progress, causing more serious health issues. For example, untreated gonorrhea or chlamydia might cause infertility in women, while untreated syphilis can lead to complications such as neurological damage or heart problems. Some infections like herpes or HIV may require specialized antiviral treatments to manage symptoms and prevent transmission to others, which can’t be done effectively without professional medical care.

5. Limited Support for Severe Cases

   At-home STD tests may not be suitable for people who have severe symptoms or are dealing with more complex cases. For example, if you are experiencing pain, sores, or discharge, you would require immediate medical attention, and an at-home test may not be sufficient to address your situation. At-home STD tests are typically limited to basic screenings and may not be able to detect these complications or provide you with the necessary medical intervention.

6. Risk of False Negatives/Positives

   Even though at-home STD tests use clinically validated methods, there can still be a possibility of receiving false negative or false positive results. False negatives may happen when the test fails to detect an infection despite it being present, while false positives occur when test incorrectly indicates an infection that is not actually there.

   False negatives can occur if the sample was not collected at the right time or if the infection is in its early stages and hasn’t yet triggered detectable levels of the virus or bacteria in the sample. On the other hand, false positives can happen due to issues such as contamination of the sample, user error, or the inherent limitations of the test.

How Did We Evaluate The Best At-home STD Test?

1. Brand Reputation

   Based on our evaluation, STDcheck, Everlywell, and LetsGetChecked lead as the best at-home STD test kits. STDcheck, founded in 2002, has a strong, established reputation with over a decade of customer trust. It works with CLIA-certified labs and offers fast, accurate results with a focus on privacy. Trustpilot reviews highlight its reliability and professional service despite some concerns about pricing. Everlywell, founded in 2015, is another highly reputable brand known for its FDA-approved tests and user-friendly process. It has earned praise for its comprehensive support and quick turnaround times, though some customers report occasional delays. LetsGetChecked is also highly regarded, with positive reviews praising its accuracy, fast results, and helpful customer service. Like Everlywell, it’s known for its transparency and ease of use, but there are occasional complaints about slow results.

   On the other hand, myLAB Box, Indicaid Health, and Simple Healthkit have more mixed reputations. myLAB Box (founded in 2014) has earned praise for its variety of testing options, but reviews on Trustpilot show concerns about delayed results and customer service. Indicaid Health, a newer brand, offers affordable and discreet testing but has received some complaints about unclear instructions and slow customer support. Simple Healthkit, while offering a simple testing process, has faced criticism for lacking customer service and unclear guidance. Lastly, Uber Box and 247Labkit are newer and less established, with fewer customer reviews. Uber Box has limited recognition but positive feedback for ease of use, while 247Labkit has fewer reviews and occasional concerns about instructions and service.

2. Customer Reviews

   As per the customer reviews, our evaluation showed Indicaid Health Sexual Health 2 to be the highest-rated option, praised for its fast shipping, discreet packaging, and easy-to-follow instructions. Customers highlight the seamless testing process, from sample collection to receiving results within a few days. Its privacy and efficiency make it a top recommendation for those seeking a reliable at-home STD test, with no significant issues reported.

   Everlywell STD Test is valued for its discreet and user-friendly approach to at-home testing. Many users appreciate its convenience, though feedback on accuracy is mixed. Some customers raise concerns about inconsistent results, affecting its reliability. While it remains a private and accessible option, these inconsistencies place it below more dependable alternatives.

   Simple Healthkit Common STD Test earns positive reviews for its ease of use and quick results. However, concerns over effectiveness, delayed results, and occasional billing issues impact its ranking. Some users report not receiving results at all, while others find the test reliable. Despite these setbacks, its convenience makes it a widely used option, though with reservations.

   myLAB Box Uber Box offers fast results and strong customer support, making it a convenient choice. However, accuracy concerns and inconsistencies in test results lower its reliability. Some users report false negatives or inaccurate readings, while others experience delayed communication. These issues make it a less dependable choice compared to higher-ranked options.

   LetsGetChecked STD Testing provides a private and accessible at-home screening experience backed by CLIA-certified and CAP-accredited labs. Users appreciate its medical-grade accuracy, but delays in results and occasional customer service concerns impact its overall ranking. Despite these drawbacks, its professional support from nurses and ease of use make it a solid option for at-home STD testing.

   247Labkit Standard Kit is designed for those seeking a fast, private, and accurate STD test. It screens for Chlamydia, Gonorrhea, and Trichomoniasis using urine or swab collection, with results available within 1-2 days. Customers appreciate the discreet packaging and prompt results. Though it has fewer customer reviews compared to competitors, its efficiency and privacy make it a reliable choice.

   STDcheck stands out for its lab-based STD testing, providing accurate and confidential results. Users order tests online and visit partner labs for sample collection, with results available within 1-2 days. It boasts high customer satisfaction on Trustpilot, an A+ Better Business Bureau(BBB) rating, and positive feedback for its reliability. While it requires an in-person visit, its accuracy and quick turnaround make it a preferred option for comprehensive STD testing.

3. Value For Money

   As per our evaluation, myLAB Box Uber Box is the most expensive at $199, or $179.10 with a subscription. It offers comprehensive testing, but better-value alternatives exist. Everlywell STD Test costs $169, providing a mid-range option, but other brands offer broader screenings for a similar price. LetsGetChecked Complete 8 Kit is the most extensive at $249, but its high price makes it less appealing compared to other multi-test kits.

   Indicaid Health Sexual Health 2 costs $99 and only covers gonorrhea and chlamydia, making it a decent but limited choice. 247Labkit Standard Kit, priced at $99.88, includes tests for chlamydia, gonorrhea, and trichomoniasis, offering slightly better value. Simple Healthkit Common STD Test is the most affordable at $69.99 with free shipping, ideal for those seeking a budget-friendly option with basic coverage.

   STDcheck 10 Test Panel at $139 offers the best balance of price, test coverage, and flexibility. With a strong reputation and customizable options, it provides the best value for those seeking a reliable and cost-effective STD screening.

Frequently Asked Questions

1. Can I get tested for all STDs at home?
   At-home tests generally cover common STDs such as chlamydia, gonorrhea, syphilis, and HIV. However, some tests may not include rare infections like hepatitis or herpes, so you may need to look for specialized testing.
2. Are at-home STD tests confidential?
   Yes, reputable at-home STD test providers ensure confidentiality. Results are delivered directly to you and are not reported to insurance or placed on your medical records.
3. Does insurance cover at-home STD tests?
   Generally, at-home STD tests are not covered by insurance, as they are considered an out-of-pocket expense.
4. Are at-home STD tests reliable?
   Yes, at-home STD tests can be reliable when taken correctly using FDA-approved methods and CLIA-certified labs.

Conclusion

At-home STD testing may offer you a convenient, private, and accessible way to monitor your sexual health. The myLAB Box, Everlywell, and LetsGetChecked can provide you with comprehensive test kits for common infections, secure online results, and telemedicine consultations for treatment when necessary.

However, it’s important to recognize that at-home tests may not cover all STDs, such as herpes or HPV, and their accuracy depends on proper sample collection. While consultations are available for positive results, immediate medical support for urgent concerns is not provided.

At-home STD tests in 2025 offer a reliable solution for regular screening, but you must be mindful of potential gaps and ensure correct sample handling. Regular testing is crucial for maintaining long-term sexual health.