Published On By Rachel Nall

Ibutamoren MK677 Review

Ibutamoren MK-677, also known as MK-677 or MK-0677, belongs to a class of compounds called growth hormone secretagogues(GHS). It stimulates human growth hormone(GH) release from the pituitary gland. Initially developed to treat diseases related to low growth hormone secretion, it is commonly misused in the fitness and bodybuilding community for its potential muscle-building and fat-burning effects.

Ibutamoren is a highly restricted substance not approved by the FDA for general consumption due to its severe side effects. The WADA and the NCAA also ban its usage in professional sports due to its performance-enhancing abilities.

It may be found in products marketed as dietary supplements; however, awareness of the potential health risks Ibutamoren poses is essential. Here, we discuss the mechanism of action, possible side effects, and alternative options for Ibutamoren.

What is Ibutamoren MK 677?

Ibutamoren MK 677 is a growth hormone secretagogue (GHS) with potent bodybuilding properties by activating ghrelin receptors.

It is known for its ability to stimulate the growth hormone and insulin-like hormone in the body, making it an effective compound for muscle growth.

Moreover, ibutamoren can have strong effects on lipolysis, which can aid in fat loss.

However, Ibutamoren is not approved for human consumption by the FDA. It is an investigational new drug with several life-threatening side effects. It is illegal to possess or use without a prescription.

How Does Ibutamoren MK 677 Work?

Activation of GHS receptors by a compound known as Ibutamoren stimulates the secretion of growth hormone and promotes lipolysis, potentially leading to increased muscle growth and fat loss. The mechanism of action of Ibutamoren MK 677 involves its interaction with the ghrelin receptor in the brain, which is responsible for sending hunger signals and regulating other emotional states.

Here are five key points about how Ibutamoren MK 677 works:

  • Activation of GHS receptors: Ibutamoren binds to and activates the ghrelin receptors in the brain, mimicking the effects of the ghrelin hormone.
  • Growth hormone secretion: By activating GHS receptors, Ibutamoren helps in stimulating the production of the growth hormone, which plays a major role in various physiological processes, including muscle growth and repair.
  • Lipolysis promotion: Ibutamoren also promotes lipolysis, which is the breakdown of stored fat cells. It can contribute to fat loss and improved body composition.
  • Increased insulin-like growth factor 1 (IGF-1) levels: The elevated growth hormone levels induced by Ibutamoren lead to an increase in circulating levels of insulin-like growth factor 1 (IGF-1), which may support muscle growth and recovery.
  • Potential for enhanced performance: Given its ability to stimulate muscle growth and promote fat loss, it is speculated that Ibutamoren may have potential benefits for athletes looking to improve their fitness and physical performance.

Ibutamoren MK 677 Benefits

  1. Promote Muscle Mass

    Ibutamoren MK 677 has been shown to stimulate the body's release of growth hormone (GH). This increase in GH levels can have a profound impact on muscle growth and development. By activating the ghrelin receptor, Ibutamoren MK 677 encourages the secretion of more GH, leading to enhanced protein synthesis within muscles.

    With increased protein synthesis, our bodies can build and repair muscles more effectively. It can result in accelerated muscle growth, improved strength, and faster recovery after intense workouts.

    Ibutamoren MK 677 promotes nitrogen retention in the muscles. Nitrogen is essential for building proteins, which form the foundation of muscle fibers.

  2. Increases HGH

    Studies have shown a significant increase in HGH levels, which could benefit those seeking to enhance their fitness journey. Higher levels of HGH play a crucial role in promoting muscle mass. This hormone stimulates protein synthesis, leading to increased muscle growth and repair.

  3. Supports Fast Recovery

    Ibutamoren mk 677 has been shown to promote rapid healing and repair of damaged tissues. It helps strengthen tendons and ligaments, reducing the risk of injuries by stimulating collagen production. Moreover, this compound also enhances muscle protein synthesis, meaning muscles can repair and grow faster.

    Ibutamoren MK 677 also claims to support body recovery by improving sleep quality.

Side Effects Of Ibutamoren MK 677

The use of Ibutamoren MK 677 has been associated with several potential side effects that should be considered. It is important to note that the frequency and severity of these side effects could vary depending on factors such as duration of use, dosage, and individual response.

  1. Increased Appetite

    Increased appetite is a commonly reported side effect associated with the use of Ibutamoren MK 677. This selective ghrelin receptor agonist has been found to increase food intake and stimulate hunger in individuals using this compound. It is important to note that while increased appetite may be desirable for certain individuals, such as those seeking to gain weight or muscle mass, it can also pose challenges for those trying to maintain or lose weight.

    The table below provides an overview of the potential effects of increased appetite associated with Ibutamoren MK 677:

    Effect Description
    Weight Gain The increased appetite caused by Ibutamoren MK 677 can lead to weight gain, particularly if caloric intake exceeds energy expenditure.
    Muscle Growth The heightened hunger induced by Ibutamoren MK 677 can lead to higher calorie consumption for individuals aiming to build muscle mass.
    Altered Metabolism The impact of increased appetite on metabolism varies among individuals. While some may experience an accelerated metabolic rate due to the additional food consumption, others may find it challenging to control their calorie intake and experience slower metabolism.

  2. Hyperglycemia

    It is a condition characterized by high blood sugar levels, is a possible side effect that can arise from using Ibutamoren MK 677. Hyperglycemia occurs when levels of glucose circulating in the bloodstream rise. It may lead to complications such as increased thirst, frequent urination, fatigue, and blurred vision. The mechanism through which Ibutamoren MK 677 may induce hyperglycemia is not fully understood. However, it may cause an increase in insulin resistance or impair glucose tolerance.

  3. Increased Blood Pressure Levels

    Ibutamoren may also cause high blood pressure by increasing vascular and stimulating sodium reabsorption. This increase in blood pressure can be due to the increased secretion of the growth hormone. Depending on the dosage, it could affect the systolic and diastolic blood pressure levels. A higher dosage could result in more pronounced fluctuations. Factors such as age, pre-existing cardiovascular conditions, other medications being used concurrently, and overall health status can influence how an individual's blood pressure responds to this compound.

  4. Insulin Resistance

    Studies have shown that Ibutamoren MK 677 may contribute to the development of insulin resistance. One study on healthy young men found that Ibutamoren MK 677 administration impaired glucose metabolism and decreased insulin sensitivity. Another study involving older people reported similar findings, demonstrating an association between Ibutamoren MK 677 use and impaired glucose tolerance.

    It is important to note that while these studies suggest a potential link between Ibutamoren MK 677 and insulin resistance, further research is needed to understand the mechanisms involved and establish causality definitively. Nonetheless, it is crucial for individuals considering or currently using this compound to be aware of these findings and monitor their blood sugar levels regularly.

  5. Lethargy

    Lethargy refers to a state of extreme tiredness or lack of energy, which can significantly impact an individual's daily activities and quality of life. It is important to note that not all individuals who take Ibutamoren MK 677 can experience lethargy as a side effect. The likelihood of experiencing lethargy may be higher at higher dosages due to the more substantial impact on hormone levels. Ibutamoren MK 677 also stimulates the release of insulin-like growth factor 1 (IGF-1) in the body, which could affect energy levels.

  6. Anxiety

    Anxiety is a state of discomfort, worry, or fear usually accompanied by symptoms such as increased heart rate, restlessness, and irritability. While the exact mechanism through which Ibutamoren MK 677 may induce anxiety is not fully understood, it is believed to be related to its effects on certain neurotransmitters in the brain.

    Ibutamoren MK 677 is known to increase the production of growth hormone and IGF-1, which can have various physiological effects. Some studies suggest that increased levels of these hormones may contribute to an increased risk of developing anxiety symptoms. Moreover, Ibutamoren MK 677 has been shown to interact with specific brain receptors that regulate mood and anxiety.

  7. Numbness

    Numbness is a loss or reduction of sensation in a particular body area. It may manifest as a tingling or a “pins and needles” sensation. The exact mechanism through which ibutamoren causes numbness has yet to be fully understood. However, it has been hypothesized that its effects on growth hormone levels may contribute to nerve compression or damage.

    It is crucial for individuals considering the use of ibutamoren to be cautious and monitor their symptoms closely. If numbness occurs while taking this compound, it is recommended to consult a trusted healthcare provider for further evaluation.

Ibutamoren MK 677 Dosage

Possessing and using Ibutamoren MK 677 is illegal without a prescription from a qualified doctor. It is prohibited from common use in the US and most of the world due to its several long-term side effects that include increased risks of cancer, stroke, liver damage, heart failure, psychosis, and infertility, to name a few. FDA has classified it as a highly restricted substance, and it is banned in professional sports by the WADA and NCAA due to its performance-enhancing abilities. There is no reliable information regarding the safe dosage of Ibutamoren MK 677.

Ibutamoren MK 677 Consumption Results

After referring to online sources and following the recommended dosage of Ibutamoren MK 677, I eagerly awaited the results. Unfortunately, my experience with Ibutamoren MK 677 was far from what I had hoped. Initially, I noticed a significant boost in strength, allowing me to lift heavier weights and easily tackle more intense workouts. But as the days passed, I constantly felt tired and irritable. My appetite decreased, and taking enough calories became an uphill task. Despite these setbacks, my trainer encouraged me to be patient and continue using it.

However, as time passed, I noticed a difference in my sexual desire, and my breasts became more pronounced, which alarmed me. My performance at the gym declined, and I started experiencing concerning side effects. These included depression, nausea, muscle cramps, trouble sleeping, and improper digestion.

Realizing that these adverse effects outweighed any potential benefits that Ibutamoren MK 677 might offer me regarding weight loss or muscle gain, I decided to stop using it altogether. It became clear that Ibutamoren MK 677 was not worth the risk and could lead to several life-threatening ailments.

Considering these factors, I decided to explore legal and natural alternatives to Ibutamoren MK 677 under the guidance of a healthcare expert.

Legal And Safe Alternative For Ibutamoren MK-677

Ibutamoren MK-677 has gained popularity among strength athletes and bodybuilders due to its purported benefits in muscle growth and performance enhancement. However, there have been concerns regarding the safety and legality of this compound. Fortunately, there are alternative options available that offer similar benefits without the associated risks.

CrazyBulk's Ibuta 677 is one such alternative, which claims to be 100% natural and free from side effects. Makers claim that by opting for this legal alternative, individuals can experience the potential advantages of increased muscle mass and improved athletic performance without compromising their integrity or exposing themselves to potentially harmful substances.

The official website says Ibuta 677 naturally increases the growth hormone, boosts vascularity, and balances mood. It claims to contain organic elements that supply your body with the required nutrients for growth. Its natural formulation could decrease the chances of any side effects, making it a safer alternative to Ibutamoren MK-677.

However, you must consult a healthcare professional before using Ibuta 677 if you have an underlying health condition. Another alternative to Ibutamoren is Ibutalean. However, their usage should be complemented with appropriate exercise and a nutritious diet.

Frequently Asked Questions

  1. Are there any long-term effects of using Ibutamoren MK 677?
    The long-term effects of using Ibutamoren MK 677 have been studied extensively. Research suggests it may increase the risk of heart attack, liver injury, and infertility. It is an unapproved drug not fit for general consumption.
  2. Can everyone use Ibutamoren MK 677?
    No one can use Ibutamoren without a prescription as it is a highly restricted substance with potential long-term side effects that can significantly impact your well-being.
  3. Is it safe to consume alcohol while taking Ibutamoren MK 677?
    Consuming alcohol while taking ibutamoren MK 677 may pose potential risks. Alcohol can negatively affect the liver, and combining it with ibutamoren MK 677, which also affects liver function, could potentially increase the risk of liver damage.
  4. How long does it take to see results from using Ibutamoren MK 677?
    Results from using Ibutamoren MK 677 can vary among individuals based on factors such as dosage, duration of use, and individual metabolism. However, it is essential to note that it is an investigational drug still not meant for human use.
  5. Can Ibutamoren MK 677 be used as a performance-enhancing drug for athletes?Ibutamoren MK 677 should not be used by athletes as the WADA and the NCAA ban it due to its performance-enhancing effects. Athletes resorting to this harmful drug put their health at risk.


Ibutamoren MK 677 is a potent compound with potential benefits for muscle growth and overall well-being. Its mechanism of action stimulates the release of growth hormone, leading to increased muscle mass and improved recovery. However, limited studies have been done on its long-term effects on the human body, making it a risky substance. It is essential to be aware of its side effects, such as increased appetite and numbness, to name a few.

It is a prohibited and illegal substance that is still being misused widely. While there may be scams in the market, legal and safe alternatives claiming similar benefits without the associated health risks are available. It is essential to consult a trusted healthcare professional before incorporating any supplement into your diet.

Leave a Reply

Your email address will not be published. Required fields are marked *