Contents
- What Is DIM Supplement?
- 8 Best DIM Supplements
- How Does DIM Supplement Work?
- How To Choose The Best DIM Supplements?
- Potential Side Effects Of DIM Supplements
- Are DIM Supplements Safe?
- Frequently Asked Questions
- Conclusion
Diindolylmethane, or DIM compound, is found in vegetables like broccoli, kale, and cauliflower. It may help balance your hormones by supporting healthy estrogen levels.
DIM may help support hormonal balance, ease symptoms related to fluctuations, and contribute to overall well-being by promoting a healthy balance of key hormones like testosterone and estrogen.
Taking DIM supplements may balance your hormones, improve your skin, support fat metabolism, and possibly reduce oxidative stress. It’s important to follow the recommended dosage for DIM, as taking too much could affect your hormone levels. You might also experience mild side effects like headaches, stomach discomfort, or changes in urine color.
This article will review the 8 best DIM supplements on the market. We’ll also look at their quality, ingredients, and reviews to help you find the one that works best for you.
What Is DIM Supplement?
Diindolylmethane compound is formed during the digestion of cruciferous vegetables such as cauliflower or kale. When these vegetables are broken down, they release indole-3-carbinol (I3C), which is further metabolized in the stomach to form DIM. This compound plays a significant role in modulating estrogen metabolism. Taking DIM supplements may help your body metabolize estrogen by promoting its conversion into 2-hydroxyestrone. It also reduces the production of less favorable metabolites, such as 16-alpha-hydroxyestrone, which could cause hormonal imbalances. This balance may support healthier hormonal activity. DIM exhibits anti-inflammatory and antioxidant properties. Thus, including DIM products in your routine may help decrease oxidative stress by helping neutralize free radicals, which can impair your cells and cause chronic diseases.
8 Best DIM Supplements
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Now DIM 200 Capsules
Now DIM 200 Capsules may help support your body’s natural metabolism and hormonal balance. It could also help promote detoxification, which is essential for removing environmental toxins from your body.
As per the official website, Now DIM 200 Capsules include calcium-D-glucarate, which plays a role in a process called glucuronidation. This process may help eliminate toxins and support overall detox health.
Now DIM 200 Capsules are said to be free from allergens like dairy, eggs, gluten, soy, and GMOs. The makers state that Now DIM 200 Capsules are produced in a GMP-certified facility, potentially adhering to high quality and safety standards.
Pros & Cons
Pros
- It may promote detoxification by aiding your body’s natural detox processes.
- It includes calcium-D-glucarate, which might help eliminate environmental toxins.
- It is free from common allergens like dairy, gluten, soy, and GMOs.
- It is made in a GMP-certified facility, ensuring quality and safety.
- It is dairy-free, egg-free, gluten-free, and soy-free.
Cons
- You might not notice changes right away, which can be frustrating if you’re looking for quick improvements.
- You could experience mild digestive discomfort or headaches, which might detract from the overall experience.
- Since the capsules are unflavored, they may not be as appealing if you’re sensitive to taste.
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Nutricost DIM Capsules
As per the makers, Nutricost DIM Capsules provide 300mg of DIM per capsule, which may support your hormone metabolism. With the added bioperine (5mg per serving), it could enhance absorption, helping your body get the most out of each dose.
Nutricost DIM Capsules may help balance your hormones, potentially giving you a sense of stability and revitalization over time. It may also support your skin health by promoting balance within your body and boosting its natural defenses.
These capsules are said to be gluten-free, non-GMO, and vegetarian and have been third-party tested for quality. Made in a GMP-compliant, FDA-registered facility, Nutricost DIM Capsules meet high safety standards to ensure optimal safety.
Pros & Cons
Pros
- Contains BioPerine to enhance absorption for better effectiveness.
- It might help support skin health by balancing the body’s natural defenses.
- Extra-strength 300mg of DIM per capsule for a more potent dose.
- It’s gluten-free, non-GMO, and vegetarian-friendly.
- It’s third-party tested to ensure quality and potency.
- Made in a GMP-compliant, FDA-registered facility for safety.
Cons
- The higher dosage may not be suitable for you.
- Results might vary for you, and benefits may take time to show.
- It might not be suitable for you if you have certain allergies or sensitivities.
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Jarrow Capsules DIM + CDG Supplement
Jarrow Formulas DIM + CDG Supplement claims to support your body’s detoxification processes and promote healthy hormones. It could support the detoxification of estrogen by aiding in liver 2-hydroxylation.
According to the official website, Jarrow Formulas DIM + CDG Supplement has CDG, which may support your liver’s glucuronidation process, helping remove toxins and supporting overall hormone health. It might also help maintain a healthy hormonal balance like testosterone, potentially supporting detoxification and hormone regulation.
The makers advise taking one Jarrow Formulas DIM + CDG capsule per day with food for the best results. It is said to be made in a facility that follows Current Good Manufacturing Practices, ensuring optimal safety.
Pros & Cons
Pros
- It may support healthy testosterone balance.
- Contains DIM and CDG, which work together to aid detoxification pathways.
- It is said to be vegan, non-GMO, and gluten-free.
- It could support liver function and toxin elimination.
- Manufactured following Current Good Manufacturing Practices (cGMP).
- It comes in capsule form, which makes it easier to include in your daily routine.
Cons
- Requires consistent use for optimal absorption and effectiveness.
- It may not be appropriate for you if you have specific hormonal conditions without medical advice.
- You might find it costlier as compared to other DIM products.
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Thorne Hormone Advantage
Thorne Hormone Advantage is said to combine diindolylmethane (DIM), pomegranate extract, and sulforaphane glucosinolate (SGS) from broccoli seed extract, which may help your body naturally process and eliminate excess estrogen. It could also boost your energy, improve physical fitness, and assist with weight management by supporting hormonal balance, leaving you feeling more balanced and revitalized. According to the official website, Thorne Hormone Advantage might help ease your mood swings, reduce physical discomfort related to hormone imbalances, and help you experience a smoother monthly cycle.
Pros & Cons
Pros
- The formula might protect your body from oxidative stress with the help of pomegranate and broccoli seed extracts.
- You could notice relief from hormone-related physical discomfort and mood swings.
- Thorne’s 60-day satisfaction guarantee allows you to try the supplement risk-free.
- Thorne products adhere to strict manufacturing practices, ensuring you are getting a safe formula.
Cons
- You might experience minor digestive discomfort or headaches as your body adjusts.
- The hypromellose capsule might not be suitable for you if you prefer supplements in powder or gummy form.
- It might interact with your current medication, so it’s important to consult a healthcare professional.
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Puritan’s Pride DIM Complex
Puritan’s Pride DIM Complex claims to support hormone processing and promote cellular health. Each capsule provides 100 mg of the DIM blend complex, delivering 25 mg of Diindolylmethane (DIM).
Puritan’s Pride DIM complex could help reduce the effects of estrogen dominance, like mood swings, breast tenderness, or weight gain. This may lead to a smoother and more balanced hormonal cycle.
The makers state that Puritan’s Pride DIM Complex might also support cellular health by helping your body process and eliminate excess female hormones, which could promote better energy levels and metabolism.
Pros & Cons
Pros
- The “buy 1, get 2” deal gives you three bottles at an affordable price.
- No artificial additives, preservatives, or allergens like gluten, dairy, or soy.
Cons
- It offers one potency level of 25 mg DIM).
- It contains gelatin.
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Seeking Health DIM + I3C
Seeking Health DIM + I3C might support liver metabolism. It may help your body detoxify and eliminate harmful substances while also supporting healthy inflammation and protecting your cells.
As per the official website, Seeking Health DIM + I3C includes Indole-3-Carbinol (I3C), which could help keep your hormone levels balanced and support your body’s response to environmental toxins, known as xenoestrogens.
It is also said to combine l-carnitine, alpha-lipoic acid, CoQ10, flavonoids, and PQQ. These nutrients may help boost your energy, support healthy aging, and improve brain function.
According to the makers, Seeking Health DIM + I3C is bioavailable and has been third-party tested for quality, ensuring it’s free from harmful bacteria, yeasts, molds, and heavy metals.
Pros & Cons
Pros
- It’s third-party tested for quality and free from harmful bacteria, yeasts, molds, and heavy metals.
- Made in the USA, ensuring high-quality manufacturing standards.
- Contains bioavailable ingredients that your body may easily absorb.
- It might assist in reducing oxidative stress and support healthy inflammatory responses.
Cons
- It may not be suitable for you if you’re allergic or sensitive to any of the ingredients.
- You might not see noticeable results right away, and you could need to take it for a longer time.
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Nature’s Craft DIM For Men
According to the official website, Nature’s Craft DIM for Men could support hormonal balance, prostate health, and overall men’s wellness. It is said to contain astragalus, panax ginseng extract, and grapeseed, which may boost your energy and vitality. The makers also included Bioperine in Nature’s Craft DIM for Men to improve absorption, helping your body get the most from these ingredients. Nature’s Craft DIM for Men may improve your performance, energy, and drive, giving you longer-lasting results. It could also help you feel more balanced and stable, supporting better mood and focus.
Pros & Cons
Pros
- It could help boost your energy levels and improve your drive.
- Contains powerful ingredients like Panax ginseng, astragalus, and grapeseed.
- Bioperine is included to enhance absorption and effectiveness.
- It is quality-tested by third parties for purity and safety.
Cons
- It might give you a temporary energy boost that might not last longer.
- It may not be suitable for you if you’re sensitive to panax ginseng or grapeseed.
- It is only available in one form, which might not meet your specific needs.
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SMNutrition DIM 200 mg
DIM 200 by SMNutrition claims to help you balance your hormones and manage symptoms like menstrual discomfort, bloating, or mood swings. It could also support you with hormonal breakouts, weight fluctuations, hot flashes, night sweats, and sleep disruptions.
As per the creators, SMNutrition DIM 200 mg might make you feel more comfortable and stable by helping to regulate your hormone levels. It is said to be third-party tested by Intertek Labs to ensure its quality and safety.
The official website highlights that SMNutrition DIM 200 mg is certified by the Gluten Intolerance Group and the Non-GMO Project, and it’s vegan, soy-free, and dairy-free. It is said to be free from common allergens like titanium dioxide and silicon dioxide.
Pros & Cons
Pros
- It may assist in addressing hormonal issues that lead to skin problems.
- It could also help manage symptoms like hot flashes and night sweats.
- It is free from common allergens like gluten, soy, and dairy.
- Certified vegan and non-GMO.
- It is third-party tested to ensure product quality and reliability.
- It comes in capsule form, allowing you to combine them seamlessly into your daily routine.
Cons
- You might find the dosage too high, causing potential side effects like nausea and headaches.
- It is only available through its official website, limiting its accessbilities.
- Even though it’s free from common allergens, it might still not be suitable for you if you have specific allergies.
How Does DIM Supplement Work?
DIM products may work by targeting estrogen metabolism and supporting critical cellular signaling pathways for hormone regulation and overall health. They might interact with your liver’s enzyme systems after consumption, particularly cytochrome P450 enzymes, to influence the breakdown of female hormones into specific metabolites.
DIM could also help modulate NF-κB signaling and reduce reactive oxygen species (ROS), which lowers oxidative stress that can damage your cells, including DNA, proteins, and lipids. They may support signaling pathways, such as the aryl hydrocarbon receptor (AhR) and MAPK pathways, which are involved in controlling the cell cycle, apoptosis, and immune response.
DIM supplements could help maintain hormone balance, reduce inflammation, and protect your cells against oxidative damage, potentially supporting your hormonal health, cellular integrity, and metabolic function.
How To Choose The Best DIM Supplements?
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Added Ingredients And Dosage
You should look at the added ingredients because they can help improve or support the effects of DIM products. For better absorption, choose supplements with black pepper extract (piperine) or Bioperine, which may help your body absorb DIM more effectively. Some supplements also include vitamins like vitamin E, vitamin D, or zinc, which could help balance your hormones. Always check the label to make sure the ingredients are safe and beneficial, and avoid products with unnecessary fillers or preservatives.
DIM supplements usually range up to 200 mg per day and could be easily tolerable. However, a higher dose of above 300mg per day might cause headaches and nausea. The right dosage depends on your health needs. Consulting with a healthcare provider could help you decide what dosage is safe for you.
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Third-Party Testing
Make sure the DIM supplement has been third-party tested. This means it has been checked for quality, safety, and effectiveness. Third-party testing makes sure that the product is free from harmful substances and reduces the chance of side effects. Always check the label or the company’s website for information about third-party testing. Look for certifications or seals that show the product has been tested.
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Form
The form of a DIM supplement can affect how well your body absorbs it. DIM supplements come in capsules, tablets, soft gels, or liquid forms, and each has its benefits. You can choose the one that works best for you.
Capsules and tablets are the most common and are easy to take and carry. However, you may find them inconvenient if you have trouble swallowing pills.
Soft gels are similar to capsules but might be easier for you to swallow and break down faster in your stomach, helping your body absorb DIM better.
Liquid DIM supplements are easier for your body to absorb and are a good option if you struggle with swallowing pills. They also let you adjust the dose more easily, especially when you’re just starting the formula for the first time.
Think about which form is most comfortable for you and fits into your routine. Make sure that the form you choose provides the right dosage for your needs.
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Reputable Brand
The brand’s reputation is essential as a trusted brand is more likely to provide a high-quality and effective product. Brands with good reputations usually follow strict quality checks, use good ingredients, and have a history of being reliable.
Look for brands that are open about where they get their ingredients and how they make their supplements. Trusted brands often share lab test results to show their products are clean and contain the right amount of DIM.
You can also explore customer reviews and ratings to see what other users have experienced with the brand’s DIM products. This will help you make an informed decision by evaluating both the advantages and drawbacks of the formula.
Potential Side Effects Of DIM Supplements
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Digestive Discomfort
You might experience digestive issues like bloating, gas, or stomach cramps when taking DIM. This happens because DIM affects your digestive system. It may increase the activity of enzymes involved in detoxification, which could disrupt your gut, especially if you’re taking it on an empty stomach or in high doses.
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Headaches
DIM could trigger hormonal changes that may lead to headaches. If you’re sensitive to these hormonal shifts, you might experience mild headaches, tension headaches, or even migraines. These headaches can feel like a dull pressure, throbbing, or sharp pain and may be accompanied by nausea or sensitivity to light and sound as your body adjusts to the hormonal changes.
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Skin Rashes Or Breakouts
Taking DIM products might cause skin breakouts or rashes. This could happen because DIM affects your hormone levels. Hormonal changes can trigger increased oil production, which may clog pores and cause acne. If your body is adjusting to the new hormone balance, it might temporarily affect your skin.
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Hormonal Fluctuations
DIM intake could lead to temporary hormonal fluctuations that might cause symptoms like mood swings, discomfort, or even irritability. Your body may need time to adjust to the changes, and these symptoms could be short-term as your hormone levels stabilize.
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Changes In Menstrual Cycle
DIM might cause temporary changes in your menstrual cycle due to its effect on your hormones. It may cause light, heavy, or more irregular periods. You could notice changes in the length or flow of your cycle or experience spotting between periods.
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Allergic Reactions
In rare cases, you might encounter an allergic reaction to DIM or another ingredient in the formula. Signs of an allergic response might include itching, swelling, hives, redness, or difficulty breathing. You may also notice a rash, feel tightness in your chest or throat, or experience dizziness or lightheadedness.
Are DIM Supplements Safe?
Since DIM is naturally found in vegetables like broccoli and kale, taking supplements can support your hormone health, especially if you’re dealing with hormonal imbalances.
However, taking too much DIM could affect your hormone levels and may cause side effects like headaches, stomach issues, or mood changes. You should follow the advised dosage and consult a healthcare provider, especially if you have any existing health conditions.
If you have hormone-sensitive conditions or take hormone-related treatments, be extra cautious, as DIM might interact with your medication or condition. Make sure to watch out for any side effects.
Frequently Asked Questions
- Can DIM Help With Breast TIssue Health?
DIM may help by promoting a healthy balance, potentially reducing the risk of estrogen dominance, which can contribute to issues like fibrocystic breast tissue. However, it’s important to consult a healthcare provider if you have specific concerns. - Does DIM Have Any Impact On Mood Or Mental Clarity?
DIM may help improve mood stability and mental clarity by promoting hormonal balance. Fluctuation in hormones can affect your mood and cognitive function, so taking DIM products may contribute to better emotional and mental health. - Can DIM Improve My Energy Levels?
DIM may support your energy levels by improving your stamina and physical performance, especially when combined with Panax ginseng and BioPerine for better absorption. However, results vary, and it isn’t a direct energy booster like caffeine.
Conclusion
DIM supplements could help balance your hormones, especially if you’re dealing with estrogen imbalances. They may also help ease issues like PMS, menopause symptoms, and acne and support prostate health.
When choosing the best DIM supplements, you should consider factors like dosage, added ingredients, the brand’s reputation, and third-party testing. You can check out the shared 8 best DIM supplements in this article to choose the one that may work well with your health goals and preferences.
To maximize your results, you can combine DIM with healthy habits like eating cruciferous vegetables, exercising, staying hydrated, and managing stress, which may support balancing your hormones and improving your energy levels.
- The information in this guide is for informational purposes only and should not be considered medical advice.
- It is not recommended to disregard/delay seeking professional medical advice or treatment because of what you read or accessed through this guide.
- The results may vary from individual to individual.
- Consult your doctor for any underlying medical conditions or if you are on any prescribed medicines before trying any product.
Rachel has been a freelance medical writer for more than 18 years. She graduated from the University of Tennessee at Knoxville in 2005 and is currently practicing as a Certified Registered Nurse Anesthetist at a Level I trauma center.
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