Best 10 Aloe Vera Supplements In 2025

Aloe vera supplements are widely used for their potential benefits in digestive support, skin health, immune function, and metabolic balance. These effects could be attributed to bioactive compounds such as acemannan found in the inner leaf gel, which have anti-inflammatory, antimicrobial, and antioxidant properties.

With so many options available, choosing the right aloe vera product could feel confusing. While some products contain higher-quality aloe extracts, others may include additional ingredients.

This list highlights the 10 best aloe vera supplements based on real consumer reviews and quality standards maintained by the brands. We have also mentioned the potential drawbacks of these supplements to help you make an informed decision.

What is Aloe Vera Supplement?

Aloe vera supplement is an oral product that contains aloe vera derived from the leaves of the plant, scientifically known as Aloe barbadensis. It contains water, vitamins (such as A, C, E, and B vitamins), minerals (including calcium, magnesium, and zinc), amino acids, polysaccharides like acemannan, and bioactive compounds.

Aloe vera supplements are available in various types, including capsules, tablets, powders, and liquids. These supplements are commonly used to enhance digestive health, enhance immune function, provide antioxidants, and promote skin health.

The inner gel content of the Aloe vera leaf is primarily used for supplements, while the latex, a yellowish substance found beneath the leaf skin, contains anthraquinones known for their laxative effects.

In 2002, the FDA banned the use of aloe latex in over-the-counter (OTC) laxatives, mentioning that aloe latex is not generally recognized as safe and effective (not GRASE) due to safety concerns. Since then, manufacturers cannot legally market OTC aloe laxatives without FDA approval through a New Drug Application (NDA), which has not been granted.

10 Best Aloe Vera Supplements

1. Global Healing Center Aloe Vera

   

   Global Healing Center Aloe Vera is made using organic, freeze-dried inner leaf gel, the most nutrient-rich part of the aloe plant. The aloe is processed to preserve a high concentration of acemannan, a potent polysaccharide that may support digestive function, balance the immune system, and calm irritated tissues.

   As per the official website, each Global Healing Center Aloe Vera capsule delivers 180 mg of inner leaf aloe vera in a potent form. This formula claims to support digestion by aiding in the optimal breakdown of food and improving nutrient absorption.

   The makers state that the natural enzymes in Global Healing Center Aloe Vera could help enhance digestive efficiency, while its prebiotic properties might help grow and sustain beneficial gut bacteria. This might lead to a healthier gut environment and fewer issues like bloating, indigestion, or discomfort after meals.

   Global Healing Center Aloe Vera may also help calm your digestive lining due to its anti-inflammatory and antimicrobial effects, offering relief from occasional constipation and promoting regularity.

   According to the official website of Global Healing Center, Aloe Vera might also help support immune function. It contains compounds like antioxidants and vitamins that may work together to strengthen the body’s defenses. Nutrients such as bradykinase and acemannan in this formula are thought to help modulate immune responses, keeping them balanced and effective.
   

   Pros

   • May support wound healing from the inside.
   • Often used to soothe gastric irritation.
   • Can help maintain hydration due to mucilaginous content.

   Cons

   • Results could vary significantly from person to person.
   • Some people may experience gastrointestinal discomfort.

2. NatureCity True-Aloe

   

   As per the manufacturer, NatureCity TrueAloe delivers a highly potent form of aloe vera in convenient capsule form, made exclusively from USDA-certified organic inner leaf gel. It claims to contain the nutritional power of over 10 pounds of fresh organic aloe leaves, providing 120 easy-to-swallow capsules.

   The makers state that the aloe used in NatureCity TrueAloe is grown on the USDA-certified organic aloe farm in Jaumave without the use of pesticides, herbicides, or chemical fertilizers.

   In NatureCity TrueAloe, the leaves are hand-harvested at peak potency, then carefully hand-fileted to exclude the aloe latex. Within just two to three hours of harvesting, the aloe gel is freeze-dried using a patented process that helps retain vital heat-sensitive compounds.

   This gentle method avoids the high-heat processing that can destroy or degrade key aloe nutrients. As a result, NatureCity TrueAloe maintains the biological complexity of aloe vera, including an estimated 200 active compounds such as vitamins, minerals, amino acids, and enzymes.

   The official website highlights that NatureCity TrueAloe is certified for content and purity as per the International Aloe Science Council (IASC) and is organically certified by QAI. This formula may support balanced stomach acid levels, aid digestion, and aid in the growth of beneficial gut bacteria. It might also help maintain healthy cholesterol levels and blood sugar levels, support joint comfort, reduce oxidative stress, and contribute to immune health.
   

   Pros

   • May support liver detoxification.
   • Contains polysaccharides that may boost immune function.
   • Offers antioxidant properties.

   Cons

   • Prolonged use may lead to electrolyte imbalance.
   • Capsules could be difficult to swallow for some users.

3. Designs for Health Aloe

   

   Designs for Health Aloe/200x might support gastrointestinal health, microbial balance, and healthy inflammatory responses in both the gut and skin.

   As per the official website, each Designs for Health Aloe/200x capsule contains 500 mg of aloe vera extract made from Aloe barbadensis inner leaf gel, using a potent 200:1 concentration ratio.

   Designs for Health Aloe/200x preserves the natural integrity of the aloe plant through its product process. The extract is never filtered and never heated above 99°F during dehydration. This low-temperature approach may help maintain the long-chain polysaccharides in their original form, compounds that are key to aloe’s immune-supporting and gut-soothing benefits.

   The makers state that when used regularly, Designs for Health Aloe/200x may help promote a healthy gut environment by supporting microbial balance and soothing the gastrointestinal tract. It might also assist in calming your skin through its natural anti-inflammatory properties.
   

   Pros

   • Provides trace vitamins like A, C, and E.
   • Can act as a mild natural laxative.
   • May promote collagen synthesis.

   Cons

   • May interact with medications like diuretics or diabetes drugs.
   • Some users may find the aftertaste unpleasant.

4. Nutricost Aloe Vera

   

   Nutricost Aloe Vera provides 20,000 mg of aloe vera leaf equivalent per capsule derived from a 200:1 concentrated extract. The formula is said to be free from GMOs, gluten, and unnecessary additives.

   As per the official website, the aloe vera used in Nutricost’s formula is concentrated to retain its rich profile of bioactive compounds, which might work together to support digestive health, soothe occasional inflammation in the gastrointestinal tract, and promote regularity.

   Nutricost Aloe Vera might also help maintain a balanced gut microbiome, support your body’s natural detoxification processes, and contribute to healthier-looking skin due to its antioxidant and hydrating properties.
   

   Pros

   • Could help reduce oral inflammation.
   • Potentially supports microbiome balance.
   • May help maintain normal blood sugar levels.

   Cons

   • Quality and purity can vary across batches.
   • Some people may find the product costly.

5. Now Aloe Vera Gels

   

   Now Aloe Vera SoftGels may provide you with a concentrated form of aloe vera to support digestive function and your body’s natural healing processes. It contains 100 mg of a 200:1 aloe vera inner leaf extract per capsule, equivalent to 20,000 mg of aloe vera gel.

   Now Aloe Vera Softgels are said to be made using organic inner leaf extract, which means the product avoids the harsh anthraquinones found in aloe latex that can irritate the digestive system. It may help you recover from minor internal discomfort and strengthen mucosal tissues like those lining the gastrointestinal tract.

   The makers state using softgels in Now Aloe Vera, which ensures that the aloe remains protected from oxidation, potentially preserving more of its active compounds until absorption.

   Now Aloe Vera Softgels might also help reduce occasional inflammation, due to aloe’s natural anti-inflammatory components such as acemannan. These properties might offer comfort if you are experiencing gut sensitivity from diet or stress.
   

   Pros

   • Can soothe heartburn in some people.
   • May promote bowel regularity when taken correctly.
   • Might help calm internal inflammation.

   Cons

   • Risk of allergic reactions in sensitive individuals.
   • Overuse may lead to dependency on bowel movements.

6. Aloe’s Best Aloe Vera

   

   According to the official website, Aloe’s Best Aloe Vera may help enhance skin clarity or manage inflammation naturally. This formula contains 120 vegetable capsules, delivering 360 mg of certified organic whole leaf aloe per capsule, providing a potent 720 mg per serving of two capsules.

   Aloe’s Best Aloe Vera formula may support the production and maintenance of keratin, the structural protein that forms both hair and nails. The makers state that with regular use, you may notice less breakage, stronger nail growth, and shinier, more resilient hair, especially when combined with a balanced diet.

   Aloe’s Best Aloe Vera could help maintain the protective lining of your stomach and intestines. Its prebiotic compounds could also promote a more balanced gut microbiome, which has a critical role in digestion, nutrient absorption, and even immune health. If you’re prone to occasional bloating or irregularity, this formula may offer gentle, plant-based support for digestive balance.

   The addition of Certified Plus Aloe Vera PL Qmatrix® QM 100X in Aloe’s Best Aloe Vera, a high-quality aloe extract made in the USA, further enhances the supplement’s bioavailability and effectiveness.
   

   Pros

   • Can provide a gentle source of plant-based enzymes.
   • May improve nutrient absorption in the gut.
   • Could support cholesterol management.

   Cons

   • May lower blood sugar levels excessively in people with diabetes.
   • Risk of dehydration due to laxative effects.

7. Puritan’s Pride Aloe Vera Extract

   

   Puritan’s Pride Aloe Vera Extract contains 25 mg of a concentrated 200:1 aloe vera gel extract, equivalent to 5,000 mg of pure inner leaf gel, or about one teaspoon of fresh aloe. It is formulated to support various aspects of gut function using the inner leaf gel of the aloe vera plant, which is known for its naturally soothing and hydrating properties. This formula could help protect your gut barrier and prevent it from becoming overly permeable, commonly referred to as leaky gut.

   According to the official website, Puritan’s Pride Aloe Vera Extract may help soothe the digestive tract, support adequate nutrient absorption, and contribute to a healthy gut lining. It may support your body’s natural healing response.
   

   Pros

   • May ease discomfort associated with hemorrhoids.
   • Can act as a natural alkalizing agent.
   • May reduce oxidative stress on skin cells

   Cons

   • May interfere with the absorption of certain nutrients.
   • You could experience headaches or fatigue during the initial use.

8. NusaPure Aloe Vera

   

   As per the official website, NusaPure Aloe Vera is claimed to be enhanced with BioPerine® for improved nutrient absorption, which ensures your body can effectively utilize the beneficial compounds found in aloe vera.

   NusaPure Aloe Vera may help support your immune function and skin repair. It could help soothe the gastrointestinal tract, support a healthy gut lining, and reduce occasional inflammation.

   The makers state that NusaPure Aloe Vera may help your body respond to daily stressors. It might aid in maintaining a stronger immune defense by supporting white blood cell activity and reducing oxidative stress.
   

   Pros

   • Can help improve hair texture when taken regularly.
   • Supports healthy pH levels in the digestive tract.
   • May promote a healthier skin tone.

   Cons

   • May cause liver toxicity in rare cases.
   • Taste and smell could be off-putting for some.

9. Botanic Choice Aloe Vera

   

   According to the official website, Botanic Choice Aloe Vera is sourced from Cape Aloe (Aloe ferox Miller). It provides 500 mg of aloe powder derived from the leaf and latex per capsule, known for its natural cleansing and soothing properties.

   Botanic Choice Aloe Vera could help calm your digestive system, especially if you occasionally deal with bloating, cramping, or irregular bowel movements. If you often feel heavy or uncomfortable after meals, this formula may help ease that sensation by supporting smoother digestion and reducing occasional irritation in the gut lining.

   The makers highlight that Botanic Choice Aloe Vera may help your liver function more efficiently. This could mean you feel less sluggish, especially if you tend to consume processed foods or alcohol regularly, as the liver is better supported in breaking down and eliminating waste.

   Botanic Choice Aloe Vera might assist your body in breaking down food, which might lead to better nutrient absorption. This is especially beneficial if you feel like you don’t get the most from your meals or often feel low on energy. Improved digestion can help you feel lighter, more energized, and less bogged down after eating.

   Botanic Choice Aloe Vera contains enzymes such as lipase, amylase, and bradykinase that might assist in breaking down fats, carbohydrates, and proteins.
   

   Pros

   • Might help reduce bloating or gas.
   • May assist in soothing irritable bowels.
   • May help minimize plaque buildup in the mouth.

   Cons

   • Effects may be too mild for therapeutic needs.
   • Not a replacement for professional medical treatment.

10. Piping Rock Aloe Vera

    

    Piping Rock Aloe Vera claims to provide the equivalent of 20,000 mg of fresh inner leaf aloe vera gel per four capsules, derived from 100 mg of a 200:1 concentrated extract. Delivered in quick-release softgels, this formula could support a healthy digestive function.

    As per the official website, Piping Rock Aloe Vera is made in a GMP-certified manufacturing facility in the USA, ensuring strict quality control from sourcing to final product. It could help strengthen your immune system, which means fewer sick days or a quicker recovery when you’re feeling under the weather, as your body has better support in fighting off pathogens and inflammation. The makers state that Piping Rock Aloe Vera might help reduce joint stiffness, mild skin flare-ups, or internal irritation.
    

    Pros

    • Potentially reduces inflammation in joints.
    • May improve recovery time after illness.
    • Could support internal tissue repair.

    Cons

    • Can increase sensitivity to sunlight.
    • May lower potassium levels with chronic use.

Side Effects of Aloe Vera Supplement

1. Might Cause Abdominal Cramps

   Abdominal cramps are a common side effect of aloe vera supplements, especially those containing aloe latex, a yellowish layer under the leaf’s skin. This component is rich in anthraquinone compounds like aloin and emodin, which act as stimulant laxatives. They irritate the intestinal lining and trigger strong muscle contractions (peristalsis), often resulting in sudden, sharp lower abdominal pain. These cramps could range from mild to severe and are sometimes accompanied by bloating, gas, or an urgent need to defecate. Higher doses (over 50 mg/day of aloin) or prolonged use can intensify these symptoms and lead to colonic dependency.

2. May Cause Diarrhea

   Aloe vera supplements, particularly those containing aloe latex, might cause diarrhea because of the presence of anthraquinones like aloin. These compounds act as stimulant laxatives by increasing water and electrolyte secretion into the colon while inhibiting reabsorption. This leads to loose, frequent stools and faster intestinal transit. The severity of diarrhea varies with dosage and individual sensitivity. Prolonged or high-dose use of Aloe vera products can result in dehydration and electrolyte imbalances, particularly potassium loss, which may cause fatigue, muscle weakness, or even heart rhythm issues. Chronic use has also been linked to melanosis coli (a dark pigmentation of the colon) and potential kidney toxicity, especially in those with pre-existing kidney conditions or on diuretics.

3. Might Cause Excessive Weight Loss

   Weight loss linked to aloe vera supplements typically stems from fluid loss caused by diarrhea, not actual fat reduction. The anthraquinones in aloe latex increase bowel movement frequency and reduce nutrient absorption. This may lead to temporary decreases in body weight through dehydration and nutrient loss, often mistaken for true weight loss. Over time, chronic use can impair your body’s ability to absorb calories and essential nutrients, possibly leading to malnutrition. This form of weight loss is unsustainable and risky, especially if you are an adult, have eating disorders, or have chronic health conditions.

How Did We Evaluate The Best Aloe Vera Supplements?

1. Brand Credibility

   Brand reputation plays a key role when evaluating aloe vera supplements, especially in a market where product quality can vary widely. To assess this, we looked at each company’s years in business, background transparency, and third-party consumer feedback, particularly from Trustpilot.

   Global Healing stands out for its strong Trustpilot rating of 4.7, which may indicate positive customer experiences. Established in 1998, it also brings credibility through its doctor-led approach and focuses on organic, plant-based formulas.

   Designs for Health, founded in 1989, is highly regarded among healthcare practitioners and known for evidence-based formulations. It holds an A+ rating from the Better Business Bureau, reflecting strong business practices and customer service standards. However, the brand currently lacks a public review presence on Trustpilot, which limits transparency from general consumer feedback.

   Now Foods, with a history going back to 1968 and GMP certification, has long maintained a reputation for quality and affordability, even though it’s not listed on Trustpilot. It maintains a strong reputation with an A+ BBB rating, which reflects positive business practices, customer responsiveness, and trustworthiness.

   Based on consumer responses from Amazon, NatureCity appears to have a strong and generally positive brand reputation, especially among people managing specific health conditions like interstitial cystitis (IC), bladder pain syndrome, and digestive issues. Many people express satisfaction with the effectiveness of the brand’s products, ease of use (such as small capsule size), and quick relief from symptoms. Repeat purchases and long-term use by customers also signal trust in the brand’s consistency and product quality.

   NusaPure has built a generally positive reputation among consumers on Amazon, especially for offering supplements that are easy to take and often show helpful results. Many reviewers mention feeling better after using the products, and some are repeat buyers, which suggests a level of trust in the brand. People also appreciate the concentrated formulas and fast, well-packaged deliveries.

   However, not all experiences are positive. A few users reported no noticeable benefits after several weeks, and one mentioned an unpleasant odor that made the product hard to use. While most reviews are favorable, these issues highlight some inconsistencies in the product experience.

   Botanic Choice also holds an A+ BBB rating, indicating good customer service and complaint resolution. Although it lacks verified reviews on Trustpilot, the BBB rating suggests the company operates with integrity. However, the lack of broader online consumer feedback limits visibility into day-to-day customer experiences.

   Nutricost’s B+ rating on the BBB is notably lower than the others, which may point to more frequent or unresolved complaints. While not necessarily a concern, it may indicate room for improvement in customer interaction or complaint handling. With no Trustpilot presence, it’s harder to analyze consumer sentiment at scale.

   Puritan’s Pride received the lowest Trustpilot score among all evaluated brands, with a rating of 1.4. Common issues include poor customer service and shipping delays.

   Piping Rock raises some concerns when it comes to brand transparency and customer trust. The company currently has no Trustpilot listing, limiting access to independent consumer feedback. More notably, it holds a D- rating on the Better Business Bureau, which is a significant indicator of unresolved complaints or poor customer service. This low rating, coupled with the absence of third-party reviews, suggests you should approach the brand with caution.

   Based on Amazon customer reviews, Aloe’s Best enjoys a generally positive brand reputation, especially among users looking for a convenient, organic aloe vera supplement. Consumers repeatedly highlight the product’s USDA organic certification, lack of additives, ease of digestion, and high potency compared to traditional aloe juice.

   However, the brand’s reputation is not without limitations. A few reviewers questioned the lack of transparency regarding GMP certification or third-party testing, which introduces uncertainty about manufacturing standards. Others found the price relatively high, especially considering the recommended dosage may only last a month.

2. Value for Money

   To evaluate the best aloe vera supplements, we considered not just the advertised benefits but the actual value each product offers based on cost per serving, formulation quality, brand transparency, and ingredient sourcing.

   Puritan’s Pride offers the most economical choice with 600 softgels for $22.49, just $0.037 each, suitable for those using aloe long-term.

   Piping Rock also stands out at $9.99 for 150 softgels ($0.07 each). Nutricost is priced at $15.97 for 120 capsules, and Botanic Choice costs $13.95 for 90 capsules. Both are affordable, offering basic aloe content at under $0.15 per serving.

   NOW is available for $15.99 for 100 softgels, and NusaPure is for $24.00 for 150 capsules, following closely, balancing reasonable pricing with solid brand credibility.

   NatureCity’s True-Aloe, priced at $23.97 for 120 capsules ($0.20 each), offers added scientific backing with ACTIValoe®. Aloe’s Best is less competitive at  $39.95 for 120 capsules, $0.33 per capsule. Global Healing Center Aloe vera is priced at $37.95 for 60 capsules, and Designs for Health Aloe vera is available at $49.25 for 60 capsules, both are the most expensive, costing $0.63 and $0.82 per capsule, respectively.

Frequently Asked Questions

1. Are aloe vera capsules better than aloe juice?
   Aloe vera capsules may be more convenient and concentrated, while aloe juice provides hydration. Both forms offer benefits like better immune function, but the best choice depends on your preference and fitness needs.
2. Do aloe vera supplements support skin health?
   Yes, aloe vera products are rich in antioxidants, enzymes, and vitamins that may help improve skin hydration, elasticity, and healing from the inside out.
3. What should I look for in a high-quality aloe vera supplement?
   Look for supplements made from organic, inner leaf aloe that are certified for purity (like IASC certification) and free from aloin or latex, which can have laxative effects.
4. What does “decolorized” aloe vera mean in supplements?
   Decolorized aloe vera supplements have had the anthraquinones (like aloin) removed, reducing the risk of laxative side effects while preserving the beneficial polysaccharides.

Conclusion

Aloe vera supplements may help promote calmness and provide protective effects on your body. The 10 best aloe vera supplements featured in this article range from highly concentrated extracts to gentle inner leaf capsules, many of which avoid aloe latex to reduce the risk of laxative side effects.

However, aloe vera supplements come with some potential risks, too. Scientific evidence links the use of aloe latex or unfiltered preparations to side effects such as abdominal cramps, diarrhea, electrolyte imbalance, and potential kidney stress. Even inner leaf-only formulations may cause mild gastrointestinal discomfort or allergic reactions.

While aloe vera supplements may offer specific benefits, such as reducing inflammation or supporting internal balance, they are not necessary for everyone. Their effects can vary based on formulation and personal response. If you have pre-existing health conditions, are pregnant, or take medications, it’s important to consult a doctor before adding these aloe vera supplements to your routine.